Pandi oli peruki nilayam revolves around the life of ‘Mike Set’ Paandi (Sabarish) who runs a sound and audio equipments shop in his small town located in Dindigul. Impressed with his manliness and character, Valarmathi (Sunaina), a rich girl from a rich family falls in love with him. Overcoming all the difficulties, finally, their marriage is set to be arranged. However, unfortunately, Paandi meets with an accident and loses all his memory and senses. Can he get back to his normalcy and will his marriage with Valarmathi take place somehow?
